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Planarians recruit piRNAs for mRNA turnover in adult stem cells

PIWI proteins utilize small RNAs called piRNAs to silence transposable elements, thereby protecting germline integrity. In planarian flatworms, PIWI proteins are essential for regeneration, which requires adult stem cells termed neoblasts. Here, we characterize planarian piRNAs and examine the roles...

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Detalles Bibliográficos
Autores principales: Kim, Iana V., Duncan, Elizabeth M., Ross, Eric J., Gorbovytska, Vladyslava, Nowotarski, Stephanie H., Elliott, Sarah A., Sánchez Alvarado, Alejandro, Kuhn, Claus-D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824462/
https://www.ncbi.nlm.nih.gov/pubmed/31537626
http://dx.doi.org/10.1101/gad.322776.118