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Planarians recruit piRNAs for mRNA turnover in adult stem cells
PIWI proteins utilize small RNAs called piRNAs to silence transposable elements, thereby protecting germline integrity. In planarian flatworms, PIWI proteins are essential for regeneration, which requires adult stem cells termed neoblasts. Here, we characterize planarian piRNAs and examine the roles...
Autores principales: | Kim, Iana V., Duncan, Elizabeth M., Ross, Eric J., Gorbovytska, Vladyslava, Nowotarski, Stephanie H., Elliott, Sarah A., Sánchez Alvarado, Alejandro, Kuhn, Claus-D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824462/ https://www.ncbi.nlm.nih.gov/pubmed/31537626 http://dx.doi.org/10.1101/gad.322776.118 |
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