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Analysis of the structural variability of topologically associated domains as revealed by Hi-C
Three-dimensional chromosome structure plays an integral role in gene expression and regulation, replication timing, and other cellular processes. Topologically associated domains (TADs), building blocks of chromosome structure, are genomic regions with higher contact frequencies within the region t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824515/ https://www.ncbi.nlm.nih.gov/pubmed/31687663 http://dx.doi.org/10.1093/nargab/lqz008 |