Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling

Pseudorabies virus (PRV), an alphaherpesvirus closely related to Varicella-Zoster virus (VZV) and Herpes simplex type 1 (HSV1) infects mucosa epithelia and the peripheral nervous system (PNS) of its host. We previously demonstrated that PRV infection induces a specific and lethal inflammatory respon...

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Detalles Bibliográficos
Autores principales: Laval, Kathlyn, Van Cleemput, Jolien, Vernejoul, Jonah B., Enquist, Lynn W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824567/
https://www.ncbi.nlm.nih.gov/pubmed/31675371
http://dx.doi.org/10.1371/journal.ppat.1008087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824567/
https://www.ncbi.nlm.nih.gov/pubmed/31675371
http://dx.doi.org/10.1371/journal.ppat.1008087

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