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Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling
Pseudorabies virus (PRV), an alphaherpesvirus closely related to Varicella-Zoster virus (VZV) and Herpes simplex type 1 (HSV1) infects mucosa epithelia and the peripheral nervous system (PNS) of its host. We previously demonstrated that PRV infection induces a specific and lethal inflammatory respon...
Autores principales: | Laval, Kathlyn, Van Cleemput, Jolien, Vernejoul, Jonah B., Enquist, Lynn W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824567/ https://www.ncbi.nlm.nih.gov/pubmed/31675371 http://dx.doi.org/10.1371/journal.ppat.1008087 |
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