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Cytolethal distending toxin induces the formation of transient messenger-rich ribonucleoprotein nuclear invaginations in surviving cells

Humans are frequently exposed to bacterial genotoxins involved in digestive cancers, colibactin and Cytolethal Distending Toxin (CDT), the latter being secreted by many pathogenic bacteria. Our aim was to evaluate the effects induced by these genotoxins on nuclear remodeling in the context of cell s...

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Detalles Bibliográficos
Autores principales: Azzi-Martin, Lamia, He, Wencan, Péré-Védrenne, Christelle, Korolik, Victoria, Alix, Chloé, Prochazkova-Carlotti, Martina, Morel, Jean-Luc, Le Roux-Goglin, Emilie, Lehours, Philippe, Djavaheri-Mergny, Mojgan, Grosset, Christophe F., Varon, Christine, Dubus, Pierre, Ménard, Armelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824578/
https://www.ncbi.nlm.nih.gov/pubmed/31568537
http://dx.doi.org/10.1371/journal.ppat.1007921