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Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration

The epicardium and its derivatives provide trophic and structural support for the developing and adult heart. Here we tested the ability of human embryonic stem cell (hESC)-derived epicardium to augment the structure and function of engineered heart tissue (EHT) in vitro and to improve efficacy of h...

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Detalles Bibliográficos
Autores principales: Bargehr, Johannes, Ong, Lay Ping, Colzani, Maria, Davaapil, Hongorzul, Hofsteen, Peter, Bhandari, Shiv, Gambardella, Laure, Novère, Nicolas Le, Iyer, Dharini, Sampaziotis, Fotios, Weinberger, Florian, Bertero, Alessandro, Leonard, Andrea, Bernard, William G, Martinson, Amy, Figg, Nichola, Regnier, Michael, Bennett, Martin R, Murry, Charles E, Sinha, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824587/
https://www.ncbi.nlm.nih.gov/pubmed/31375810
http://dx.doi.org/10.1038/s41587-019-0197-9