Functional Characterization of Pharmcogenetic Variants of Human Cytochrome P450 2C9 in Korean Populations

Human cytochrome P450 2C9 is a highly polymorphic enzyme that is required for drug and xenobiotic metabolism. Here, we studied eleven P450 2C9 genetic variants—including three novel variants F69S, L310V, and Q324X—that were clinically identified in Korean patients. P450 2C9 variant enzymes were expr...

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Detalles Bibliográficos
Autores principales: Cho, Myung-A, Yoon, Jihoon G., Kim, Vitchan, Kim, Harim, Lee, Rowoon, Lee, Min Goo, Kim, Donghak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824622/
https://www.ncbi.nlm.nih.gov/pubmed/31484472
http://dx.doi.org/10.4062/biomolther.2019.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824622/
https://www.ncbi.nlm.nih.gov/pubmed/31484472
http://dx.doi.org/10.4062/biomolther.2019.112

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