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Role of Helix 8 in Dopamine Receptor Signaling

G protein-coupled receptors (GPCRs) are membrane receptors whose agonist-induced dynamic conformational changes trigger heterotrimeric G protein activation, followed by GRK-mediated phosphorylation and arrestin-mediated desensitization. Cytosolic regions of GPCRs have been studied extensively becaus...

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Detalles Bibliográficos
Autores principales: Yang, Han-Sol, Sun, Ningning, Zhao, Xiaodi, Kim, Hee Ryung, Park, Hyun-Ju, Kim, Kyeong-Man, Chung, Ka Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824627/
https://www.ncbi.nlm.nih.gov/pubmed/30971061
http://dx.doi.org/10.4062/biomolther.2019.026