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Understanding PDE4's function in Alzheimer's disease; a target for novel therapeutic approaches

Phosphodiesterases (PDEs) have long been considered as targets for the treatment of Alzheimer's disease (AD) and a substantial body of evidence suggests that one sub-family from the super-family of PDEs, namely PDE4D, has particular significance in this context. This review discusses the role o...

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Detalles Bibliográficos
Autores principales: Tibbo, Amy J., Tejeda, Gonzalo S., Baillie, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824677/
https://www.ncbi.nlm.nih.gov/pubmed/31642904
http://dx.doi.org/10.1042/BST20190763