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How is the acyl chain composition of phosphoinositides created and does it matter?

The phosphoinositide (PIPn) family of signalling phospholipids are central regulators in membrane cell biology. Their varied functions are based on the phosphorylation pattern of their inositol ring, which can be recognized by selective binding domains in their effector proteins and be modified by a...

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Detalles Bibliográficos
Autores principales: Barneda, David, Cosulich, Sabina, Stephens, Len, Hawkins, Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824679/
https://www.ncbi.nlm.nih.gov/pubmed/31657437
http://dx.doi.org/10.1042/BST20190205