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PD-1/PD-L1 pathway activation restores the imbalance of Th1/Th2 and treg/Th17 cells subtypes in immune thrombocytopenic purpura patients

This study aims to investigate the changes of cytokines and the effect of programmed death ligand 1 (PD-L1) signaling pathway on T cell function in patients with immune thrombocytopenic purpura (ITP). Totally, 40 untreated ITP patients were recruited and 30 healthy people were recruited as the healt...

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Detalles Bibliográficos
Autores principales: Wu, Die, Liu, Ying, Pang, Nannan, Sun, Mingling, Wang, Xiujuan, Haridia, Yasen, Zhao, Fang, Qin, Yuting, Fan, Wenxia, Guo, Xinhong, Ding, Jianbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824755/
https://www.ncbi.nlm.nih.gov/pubmed/31651870
http://dx.doi.org/10.1097/MD.0000000000017608