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A test for treatment effects in randomized controlled trials, harnessing the power of ultrahigh dimensional big data

BACKGROUND: The randomized controlled trial (RCT) is the gold-standard research design in biomedicine. However, practical concerns often limit the sample size, n, the number of patients in a RCT. We aim to show that the power of a RCT can be increased by increasing p, the number of baseline covariat...

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Detalles Bibliográficos
Autores principales: Lee, Wen-Chung, Lin, Jui-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824789/
https://www.ncbi.nlm.nih.gov/pubmed/31651877
http://dx.doi.org/10.1097/MD.0000000000017630