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Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts

Inositol Polyphosphate 4-Phosphatase, Type II (INPP4B) is a tumour suppressor in breast, ovarian, prostate, thyroid and other cancers, attributed to its ability to reduce oncogenic Akt-signaling. However, emerging studies show that INPP4B also has tumour-promoting properties in cancers including acu...

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Detalles Bibliográficos
Autores principales: Mangialardi, Emily Marie, Chen, Keyue, Salmon, Brittany, Vacher, Jean, Salmena, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824866/
https://www.ncbi.nlm.nih.gov/pubmed/31695845
http://dx.doi.org/10.18632/oncotarget.27293