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Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts
Inositol Polyphosphate 4-Phosphatase, Type II (INPP4B) is a tumour suppressor in breast, ovarian, prostate, thyroid and other cancers, attributed to its ability to reduce oncogenic Akt-signaling. However, emerging studies show that INPP4B also has tumour-promoting properties in cancers including acu...
Autores principales: | Mangialardi, Emily Marie, Chen, Keyue, Salmon, Brittany, Vacher, Jean, Salmena, Leonardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824866/ https://www.ncbi.nlm.nih.gov/pubmed/31695845 http://dx.doi.org/10.18632/oncotarget.27293 |
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