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Tyrosine kinase Eph receptor A6 sensitizes glioma‐initiating cells towards bone morphogenetic protein‐induced apoptosis

Bone morphogenetic protein (BMP) signaling plays important roles in glioblastoma multiforme (GBM), a lethal form of brain tumor. BMP reduces GBM tumorigenicity through its differentiation‐ and apoptosis‐inducing effects on glioma‐initiating cells (GIC). However, some GIC do not respond to the tumor...

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Detalles Bibliográficos
Autores principales: Raja, Erna, Morikawa, Masato, Nishida, Jun, Tanabe, Ryo, Takahashi, Kei, Seeherman, Howard J., Saito, Nobuhito, Todo, Tomoki, Miyazono, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825014/
https://www.ncbi.nlm.nih.gov/pubmed/31483918
http://dx.doi.org/10.1111/cas.14187