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Tyrosine kinase Eph receptor A6 sensitizes glioma‐initiating cells towards bone morphogenetic protein‐induced apoptosis
Bone morphogenetic protein (BMP) signaling plays important roles in glioblastoma multiforme (GBM), a lethal form of brain tumor. BMP reduces GBM tumorigenicity through its differentiation‐ and apoptosis‐inducing effects on glioma‐initiating cells (GIC). However, some GIC do not respond to the tumor...
Autores principales: | Raja, Erna, Morikawa, Masato, Nishida, Jun, Tanabe, Ryo, Takahashi, Kei, Seeherman, Howard J., Saito, Nobuhito, Todo, Tomoki, Miyazono, Kohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825014/ https://www.ncbi.nlm.nih.gov/pubmed/31483918 http://dx.doi.org/10.1111/cas.14187 |
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