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Analysis of colorectal cancer‐related mutations by liquid biopsy: Utility of circulating cell‐free DNA and circulating tumor cells

We recruited 56 colorectal cancer patients and compared the mutational spectrum of tumor tissue DNA, circulating cell‐free DNA (ccfDNA) and circulating tumor cell (CTC) DNA (ctcDNA) to evaluate the potential of liquid biopsy to detect heterogeneity of cancer. Tumor tissue DNA, ccfDNA, and ctcDNA wer...

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Detalles Bibliográficos
Autores principales: Takeda, Kohki, Yamada, Takeshi, Takahashi, Goro, Iwai, Takuma, Ueda, Koji, Kuriyama, Sho, Koizumi, Michihiro, Matsuda, Akihisa, Shinji, Seiichi, Ohta, Ryo, Yokoyama, Yasuyuki, Hotta, Masahiro, Hara, Keisuke, Yoshida, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825018/
https://www.ncbi.nlm.nih.gov/pubmed/31465598
http://dx.doi.org/10.1111/cas.14186