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Precise immunomodulation of the M1 to M2 macrophage transition enhances mesenchymal stem cell osteogenesis and differs by sex

OBJECTIVES: Up to 10% of fractures result in undesirable outcomes, for which female sex is a risk factor. Cellular sex differences have been implicated in these different healing processes. Better understanding of the mechanisms underlying bone healing and sex differences in this process is key to i...

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Detalles Bibliográficos
Autores principales: Nathan, Karthik, Lu, Laura Y., Lin, Tzuhua, Pajarinen, Jukka, Jämsen, Eemeli, Huang, Jhih-Fong, Romero-Lopez, Monica, Maruyama, Masahiro, Kohno, Yusuke, Yao, Zhenyu, Goodman, Stuart B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825050/
https://www.ncbi.nlm.nih.gov/pubmed/31728188
http://dx.doi.org/10.1302/2046-3758.810.BJR-2018-0231.R2