Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients

Germline variants such as BRCA1/2 play an important role in tumorigenesis and clinical outcomes of cancer patients. However, only a small fraction (i.e., 5–10%) of inherited variants has been associated with clinical outcomes (e.g., BRCA1/2, APC, TP53, PTEN and so on). The challenge remains in using...

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Detalles Bibliográficos
Autores principales: Milanese, Jean-Sébastien, Tibiche, Chabane, Zou, Jinfeng, Meng, Zhigang, Nantel, Andre, Drouin, Simon, Marcotte, Richard, Wang, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825127/
https://www.ncbi.nlm.nih.gov/pubmed/31701019
http://dx.doi.org/10.1038/s41698-019-0100-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825127/
https://www.ncbi.nlm.nih.gov/pubmed/31701019
http://dx.doi.org/10.1038/s41698-019-0100-7

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