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Developmental conditions modulate DNA methylation at the glucocorticoid receptor gene with cascading effects on expression and corticosterone levels in zebra finches

Developmental conditions can impact the adult phenotype via epigenetic changes that modulate gene expression. In mammals, methylation of the glucocorticoid receptor gene Nr3c1 has been implicated as mediator of long-term effects of developmental conditions, but this evidence is limited to humans and...

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Detalles Bibliográficos
Autores principales: Jimeno, Blanca, Hau, Michaela, Gómez-Díaz, Elena, Verhulst, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825131/
https://www.ncbi.nlm.nih.gov/pubmed/31676805
http://dx.doi.org/10.1038/s41598-019-52203-8