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Therapeutic potential of functionalized siRNA nanoparticles on regression of liver cancer in experimental mice

Short interfering RNA (siRNA) possesses special ability of silencing specific gene. To increase siRNA stability, transportation and its uptake by tumor cells, effective delivery to the appropriate target cells is a major challenge of siRNA-based therapy. In the present study, an effective, safe and...

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Detalles Bibliográficos
Autores principales: Khan, Azmat Ali, Alanazi, Amer M., Jabeen, Mumtaz, Chauhan, Arun, Ansari, Mohammad Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825139/
https://www.ncbi.nlm.nih.gov/pubmed/31676815
http://dx.doi.org/10.1038/s41598-019-52142-4