Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases

The endoplasmic reticulum (ER) is not only important for protein synthesis and folding but is also crucial for lipid synthesis and metabolism. In the current study, we demonstrate an important role of ceramide synthases (CerS) in ER stress and NAFLD progression. Ceramide is important in sphingolipid...

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Detalles Bibliográficos
Autores principales: Kim, Ye-Ryung, Lee, Eun-Ji, Shin, Kyong-Oh, Kim, Min Hee, Pewzner-Jung, Yael, Lee, Yong-Moon, Park, Joo-Won, Futerman, Anthony H., Park, Woo-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825147/
https://www.ncbi.nlm.nih.gov/pubmed/31676768
http://dx.doi.org/10.1038/s12276-019-0340-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825147/
https://www.ncbi.nlm.nih.gov/pubmed/31676768
http://dx.doi.org/10.1038/s12276-019-0340-1

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