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Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons

Medial ganglionic eminence (MGE)-derived somatostatin (SST)+ and parvalbumin (PV)+ cortical interneurons (CINs), have characteristic molecular, anatomical and physiological properties. However, mechanisms regulating their diversity remain poorly understood. Here, we show that conditional loss of the...

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Detalles Bibliográficos
Autores principales: Malik, Ruchi, Pai, Emily Ling-Lin, Rubin, Anna N, Stafford, April M, Angara, Kartik, Minasi, Petros, Rubenstein, John L., Sohal, Vikaas S, Vogt, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825152/
https://www.ncbi.nlm.nih.gov/pubmed/31676823
http://dx.doi.org/10.1038/s41467-019-12962-4