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Evidence that fodipir (DPDP) binds neurotoxic Pt(2+) with a high affinity: An electron paramagnetic resonance study
Oxaliplatin typically causes acute neuropathic problems, which may, in a dose-dependent manner, develop into a chronic form of chemotherapy-induced peripheral neuropathy (CIPN), which is associated with retention of Pt(2+) in the dorsal root ganglion. A clinical study by Coriat and co-workers sugges...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825159/ https://www.ncbi.nlm.nih.gov/pubmed/31676855 http://dx.doi.org/10.1038/s41598-019-52248-9 |