Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo

CD47 is a ubiquitously expressed transmembrane glycoprotein that regulates inflammatory responses and tissue repair. Here, we show that normal mice treated with anti-CD47 antibodies, and Cd47-null mice have impaired intestinal mucosal wound healing. Furthermore, intestinal epithelial cell (IEC)-spec...

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Detalles Bibliográficos
Autores principales: Reed, Michelle, Luissint, Anny-Claude, Azcutia, Veronica, Fan, Shuling, O’Leary, Monique N., Quiros, Miguel, Brazil, Jennifer, Nusrat, Asma, Parkos, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825175/
https://www.ncbi.nlm.nih.gov/pubmed/31676794
http://dx.doi.org/10.1038/s41467-019-12968-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825175/
https://www.ncbi.nlm.nih.gov/pubmed/31676794
http://dx.doi.org/10.1038/s41467-019-12968-y

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