A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor

Some lung and ovarian tumors are connected to the loss of expression of SMARCA4 gene. In its promoter region, a 44-nucleotides long guanine sequence prone to form G-quadruplex structures has been studied by means of spectroscopic techniques (circular dichroism, molecular absorption and nuclear magne...

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Detalles Bibliográficos
Autores principales: Benabou, Sanae, Mazzini, Stefania, Aviñó, Anna, Eritja, Ramon, Gargallo, Raimundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825181/
https://www.ncbi.nlm.nih.gov/pubmed/31676783
http://dx.doi.org/10.1038/s41598-019-52311-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825181/
https://www.ncbi.nlm.nih.gov/pubmed/31676783
http://dx.doi.org/10.1038/s41598-019-52311-5

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