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The HIV protease inhibitor darunavir prevents kidney injury via HIV-independent mechanisms

HIV-associated nephropathy (HIVAN) is a rapidly progressive kidney disease that is caused by HIV infection of renal epithelial cells with subsequent expression of viral genes, including vpr. Antiretroviral therapy ameliorates HIVAN without eradicating HIV from the kidneys and the mechanism by which...

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Detalles Bibliográficos
Autores principales: Gao, Xiaobo, Rosales, Alan, Karttunen, Heidi, Bommana, Geetha M., Tandoh, Buadi, Yi, Zhengzi, Habib, Zainab, D’Agati, Vivette, Zhang, Weijia, Ross, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825220/
https://www.ncbi.nlm.nih.gov/pubmed/31676833
http://dx.doi.org/10.1038/s41598-019-52278-3