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A multi-sample approach increases the accuracy of transcript assembly

Transcript assembly from RNA-seq reads is a critical step in gene expression and subsequent functional analyses. Here we present PsiCLASS, an accurate and efficient transcript assembler based on an approach that simultaneously analyzes multiple RNA-seq samples. PsiCLASS combines mixture statistical...

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Detalles Bibliográficos
Autores principales: Song, Li, Sabunciyan, Sarven, Yang, Guangyu, Florea, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825223/
https://www.ncbi.nlm.nih.gov/pubmed/31676772
http://dx.doi.org/10.1038/s41467-019-12990-0