Highly efficient ex vivo lentiviral transduction of primary human pancreatic exocrine cells

The lack of efficient gene transfer methods into primary human pancreatic exocrine cells hampers studies on the plasticity of these cells and their possible role in beta cell regeneration. Therefore, improved gene transfer protocols are needed. Lentiviral vectors are widely used to drive ectopic gen...

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Detalles Bibliográficos
Autores principales: Balak, Jeetindra R. A., de Graaf, Natascha, Zaldumbide, Arnaud, Rabelink, Ton J., Hoeben, Rob C., de Koning, Eelco J. P., Carlotti, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825235/
https://www.ncbi.nlm.nih.gov/pubmed/31676849
http://dx.doi.org/10.1038/s41598-019-51763-z