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Wnt activator FOXB2 drives the neuroendocrine differentiation of prostate cancer

The Wnt signaling pathway is of paramount importance for development and disease. However, the tissue-specific regulation of Wnt pathway activity remains incompletely understood. Here we identify FOXB2, an uncharacterized forkhead box family transcription factor, as a potent activator of Wnt signali...

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Detalles Bibliográficos
Autores principales: Moparthi, Lavanya, Pizzolato, Giulia, Koch, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825314/
https://www.ncbi.nlm.nih.gov/pubmed/31611391
http://dx.doi.org/10.1073/pnas.1906484116