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Stromal ColXα1 expression correlates with tumor-infiltrating lymphocytes and predicts adjuvant therapy outcome in ER-positive/HER2-positive breast cancer

BACKGROUND: The breast cancer microenvironment contributes to tumor progression and response to chemotherapy. Previously, we reported that increased stromal Type X collagen α1 (ColXα1) and low TILs correlated with poor pathologic response to neoadjuvant therapy in estrogen receptor and HER2-positive...

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Detalles Bibliográficos
Autores principales: Zhao, Chaohui Lisa, Singh, Kamaljeet, Brodsky, Alexander S., Lu, Shaolei, Graves, Theresa A., Fenton, Mary Anne, Yang, Dongfang, Sturtevant, Ashlee, Resnick, Murray B., Wang, Yihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825361/
https://www.ncbi.nlm.nih.gov/pubmed/31675929
http://dx.doi.org/10.1186/s12885-019-6134-y