Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release

Using non-human primates (NHPs), mice, and human primary cells, we found a role for interleukin-10 (IL-10) in the upregulation of the tissue-resident memory T cell (T(RM)) marker CD103. In NHPs, intravenous, but not subcutaneous, immunization with peptide antigen and an adjuvant combining an agonist...

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Detalles Bibliográficos
Autores principales: Thompson, Elizabeth A., Darrah, Patricia A., Foulds, Kathryn E., Hoffer, Elena, Caffrey-Carr, Alayna, Norenstedt, Sophie, Perbeck, Leif, Seder, Robert A., Kedl, Ross M., Loré, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825402/
https://www.ncbi.nlm.nih.gov/pubmed/31365858
http://dx.doi.org/10.1016/j.celrep.2019.06.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825402/
https://www.ncbi.nlm.nih.gov/pubmed/31365858
http://dx.doi.org/10.1016/j.celrep.2019.06.087

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