Exosomes derived from statin-modified bone marrow dendritic cells increase thymus-derived natural regulatory T cells in experimental autoimmune myasthenia gravis

BACKGROUND: The thymus plays an essential role in the pathogenesis of myasthenia gravis (MG). In patients with MG, natural regulatory T cells (nTreg), a subpopulation of T cells that maintain tolerance to self-antigens, are severely impaired in the thymuses. In our previous study, upregulated nTreg...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Liu, Ru-Tao, Du, Tong, Yang, Chun-Lin, Liu, Yu-Dong, Ge, Meng-Ru, Zhang, Min, Li, Xiao-Li, Li, Heng, Dou, Ying-Chun, Duan, Rui-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825716/
https://www.ncbi.nlm.nih.gov/pubmed/31679515
http://dx.doi.org/10.1186/s12974-019-1587-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825716/
https://www.ncbi.nlm.nih.gov/pubmed/31679515
http://dx.doi.org/10.1186/s12974-019-1587-0

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