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The Nudix Hydrolase 15 (NUDT15) Gene Variants among Jordanian Arab Population

BACKGROUND: Nudix Hydrolase 15 gene (NUDT15) encodes nucleotide triphosphate diphosphatase which metabolizes the purine analog drugs, such as anticancer thiopurine and anti-gout allopurinol. Genetic variants on Nudix Hydrolase 15 gene (NUDT15) gene effects the drug’s hydrolyses and hence increases t...

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Detalles Bibliográficos
Autores principales: Jarrar, Yazun Bashir, Ghishan, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825778/
https://www.ncbi.nlm.nih.gov/pubmed/30909691
http://dx.doi.org/10.31557/APJCP.2019.20.3.801