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Methods for Dealing With Missing Covariate Data in Epigenome-Wide Association Studies
Multiple imputation (MI) is a well-established method for dealing with missing data. MI is computationally intensive when imputing missing covariates with high-dimensional outcome data (e.g., DNA methylation data in epigenome-wide association studies (EWAS)), because every outcome variable must be i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825836/ https://www.ncbi.nlm.nih.gov/pubmed/31504104 http://dx.doi.org/10.1093/aje/kwz186 |