High expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival

BACKGROUND: DNA‐Dependent Protein Kinase Catalytic Subunit (PRKDC), a key component of the DNA damage repair pathway, is associated with chemotherapy resistance and tumor progression. METHODS: Here we analyzed transcriptome data of ~2,000 breast cancer patients and performed functional studies in vi...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Yang, Wei‐kang, Wen, Guo‐ming, Tang, Hongping, Wu, Chuan‐an, Wu, Yan‐xia, Jing, Zhi‐liang, Tang, Min‐shan, Liu, Guang‐long, Li, Da‐zhou, Li, Yan‐hua, Deng, Yong‐Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825841/
https://www.ncbi.nlm.nih.gov/pubmed/31513357
http://dx.doi.org/10.1002/mgg3.908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825841/
https://www.ncbi.nlm.nih.gov/pubmed/31513357
http://dx.doi.org/10.1002/mgg3.908

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