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LRRK2 N551K and R1398H variants are protective in Malays and Chinese in Malaysia: A case–control association study for Parkinson's disease

BACKGROUND: The LRRK2 gene is associated with Parkinson's disease (PD) as a number of mutations within the gene have been shown to be susceptibility factors. Studies on various global populations have determined that mutations such as G2019S, G2385R, and R1628P in LRRK2 increase the risk of dev...

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Detalles Bibliográficos
Autores principales: Gopalai, Aroma Agape, Lim, Jia Lun, Li, Hui‐Hua, Zhao, Yi, Lim, Thien Thien, Eow, Gaik B., Puvanarajah, Santhi, Viswanathan, Shanthi, Norlinah, Mohamed Ibrahim, Abdul Aziz, Zariah, Lim, Soo Kun, Tan, Chong Tin, Tan, Ai Huey, Lim, Shen‐Yang, Tan, Eng‐King, Ahmad Annuar, Azlina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825847/
https://www.ncbi.nlm.nih.gov/pubmed/31487119
http://dx.doi.org/10.1002/mgg3.604