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Targeting claudin‐4 enhances chemosensitivity of pancreatic ductal carcinomas

Claudin (CLDN) family comprises of protein that form a tight junction, and is involved in regulating polarity and differentiation of cells. Here, we aimed to investigate the effects of inhibiting CLDN4 in pancreatic ductal carcinomas (PDC). We first examined 91 cases of human PDC by immunohistochemi...

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Detalles Bibliográficos
Autores principales: Sasaki, Takamitsu, Fujiwara‐Tani, Rina, Kishi, Shingo, Mori, Shiori, Luo, Yi, Ohmori, Hitoshi, Kawahara, Isao, Goto, Kei, Nishiguchi, Yukiko, Mori, Takuya, Sho, Masayuki, Kondo, Masuo, Kuniyasu, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825989/
https://www.ncbi.nlm.nih.gov/pubmed/31498559
http://dx.doi.org/10.1002/cam4.2547