Cargando…

Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures

The upper airway epithelium, which is mainly composed of multiciliated, goblet, club and basal cells, ensures proper mucociliary function and can regenerate in response to assaults. In chronic airway diseases, defective repair leads to tissue remodeling. Delineating key drivers of differentiation dy...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiz García, Sandra, Deprez, Marie, Lebrigand, Kevin, Cavard, Amélie, Paquet, Agnès, Arguel, Marie-Jeanne, Magnone, Virginie, Truchi, Marin, Caballero, Ignacio, Leroy, Sylvie, Marquette, Charles-Hugo, Marcet, Brice, Barbry, Pascal, Zaragosi, Laure-Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826037/
https://www.ncbi.nlm.nih.gov/pubmed/31558434
http://dx.doi.org/10.1242/dev.177428