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Methionine metabolism and methyltransferases in the regulation of aging and lifespan extension across species
Methionine restriction (MetR) extends lifespan across different species and exerts beneficial effects on metabolic health and inflammatory responses. In contrast, certain cancer cells exhibit methionine auxotrophy that can be exploited for therapeutic treatment, as decreasing dietary methionine sele...
Autores principales: | Parkhitko, Andrey A., Jouandin, Patrick, Mohr, Stephanie E., Perrimon, Norbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826121/ https://www.ncbi.nlm.nih.gov/pubmed/31460700 http://dx.doi.org/10.1111/acel.13034 |
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