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Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration

The exact mechanisms leading to neurodegeneration in Alzheimer's disease (AD) and other tauopathies are not yet entirely understood. However, it is known that several RNA‐binding proteins (RBPs) form toxic aggregates and also interact with tau in such granules in tauopathies, including AD. The...

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Detalles Bibliográficos
Autores principales: Montalbano, Mauro, McAllen, Salome, Sengupta, Urmi, Puangmalai, Nicha, Bhatt, Nemil, Ellsworth, Anna, Kayed, Rakez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826126/
https://www.ncbi.nlm.nih.gov/pubmed/31532069
http://dx.doi.org/10.1111/acel.13035