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Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD‐L1)‐mediated immunosuppression

Aging is characterized by a progressive loss of physiological integrity, while cancer represents one of the primary pathological factors that severely threaten human lifespan and healthspan. In clinical oncology, drug resistance limits the efficacy of most anticancer treatments, and identification o...

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Detalles Bibliográficos
Autores principales: Xu, Qixia, Long, Qilai, Zhu, Dexiang, Fu, Da, Zhang, Boyi, Han, Liu, Qian, Min, Guo, Jianming, Xu, Jianmin, Cao, Liu, Chin, Y. Eugene, Coppé, Jean‐Philippe, Lam, Eric W.‐F., Campisi, Judith, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826133/
https://www.ncbi.nlm.nih.gov/pubmed/31493351
http://dx.doi.org/10.1111/acel.13027