Reversal of epigenetic aging and immunosenescent trends in humans

Epigenetic “clocks” can now surpass chronological age in accuracy for estimating biological age. Here, we use four such age estimators to show that epigenetic aging can be reversed in humans. Using a protocol intended to regenerate the thymus, we observed protective immunological changes, improved r...

Descripción completa

Detalles Bibliográficos
Autores principales: Fahy, Gregory M., Brooke, Robert T., Watson, James P., Good, Zinaida, Vasanawala, Shreyas S., Maecker, Holden, Leipold, Michael D., Lin, David T. S., Kobor, Michael S., Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826138/
https://www.ncbi.nlm.nih.gov/pubmed/31496122
http://dx.doi.org/10.1111/acel.13028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826138/
https://www.ncbi.nlm.nih.gov/pubmed/31496122
http://dx.doi.org/10.1111/acel.13028

Ejemplares similares