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Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15
The risk of colorectal cancer (CRC) varies between people, and the cellular mechanisms mediating the differences in risk are largely unknown. Senescence has been implicated as a causative cellular mechanism for many diseases, including cancer, and may affect the risk for CRC. Senescent fibroblasts t...
Autores principales: | Guo, Yuna, Ayers, Jessica L., Carter, Kelly T., Wang, Ting, Maden, Sean K., Edmond, Darwin, Newcomb P, Polly, Li, Christopher, Ulrich, Cornelia, Yu, Ming, Grady, William M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826139/ https://www.ncbi.nlm.nih.gov/pubmed/31389184 http://dx.doi.org/10.1111/acel.13013 |
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