Cargando…
Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts
Somatic mutations are critical for cancer development and may play a role in age‐related functional decline. Here, we used deep sequencing to analyze the prevalence of somatic mutations during in vitro cell aging. Primary dermal fibroblasts from healthy subjects of young and advanced age, from Hutch...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141/ https://www.ncbi.nlm.nih.gov/pubmed/31385397 http://dx.doi.org/10.1111/acel.13010 |