A human tissue‐specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence

Aging is the biggest risk factor for cancer, but the mechanisms linking these two processes remain unclear. Using GTEx and TCGA data, we compared genes differentially expressed with age and genes differentially expressed in cancer among nine human tissues. In most tissues, aging and cancer gene expr...

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Detalles Bibliográficos
Autores principales: Chatsirisupachai, Kasit, Palmer, Daniel, Ferreira, Susana, de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826163/
https://www.ncbi.nlm.nih.gov/pubmed/31560156
http://dx.doi.org/10.1111/acel.13041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826163/
https://www.ncbi.nlm.nih.gov/pubmed/31560156
http://dx.doi.org/10.1111/acel.13041

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