Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro‐inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to detect...

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Detalles Bibliográficos
Autores principales: Labzin, Larisa I, Bottermann, Maria, Rodriguez‐Silvestre, Pablo, Foss, Stian, Andersen, Jan Terje, Vaysburd, Marina, Clift, Dean, James, Leo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826209/
https://www.ncbi.nlm.nih.gov/pubmed/31468569
http://dx.doi.org/10.15252/embj.2018101365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826209/
https://www.ncbi.nlm.nih.gov/pubmed/31468569
http://dx.doi.org/10.15252/embj.2018101365

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