Macrophage Migration Inhibitory Factor Is a Molecular Determinant of the Anti-EGFR Monoclonal Antibody Cetuximab Resistance in Human Colorectal Cancer Cells

Background: The clinical impact of the monoclonal antibody cetuximab targeting the EGFR in colorectal cancer (CRC) is widely recognized. Nevertheless, the onset of cetuximab resistance is a serious issue that limits the effectiveness of this drug in targeted therapies. Unraveling the molecular playe...

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Detalles Bibliográficos
Autores principales: Russo, Rosita, Matrone, Nunzia, Belli, Valentina, Ciardiello, Davide, Valletta, Mariangela, Esposito, Sabrina, Pedone, Paolo Vincenzo, Ciardiello, Fortunato, Troiani, Teresa, Chambery, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826402/
https://www.ncbi.nlm.nih.gov/pubmed/31557914
http://dx.doi.org/10.3390/cancers11101430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826402/
https://www.ncbi.nlm.nih.gov/pubmed/31557914
http://dx.doi.org/10.3390/cancers11101430

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