Pharmacological Targeting of BET Bromodomain Proteins in Acute Myeloid Leukemia and Malignant Lymphomas: From Molecular Characterization to Clinical Applications

Alterations in protein-protein and DNA-protein interactions and abnormal chromatin remodeling are a major cause of uncontrolled gene transcription and constitutive activation of critical signaling pathways in cancer cells. Multiple epigenetic regulators are known to be deregulated in several hematol...

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Detalles Bibliográficos
Autores principales: Reyes-Garau, Diana, Ribeiro, Marcelo L., Roué, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826405/
https://www.ncbi.nlm.nih.gov/pubmed/31581671
http://dx.doi.org/10.3390/cancers11101483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826405/
https://www.ncbi.nlm.nih.gov/pubmed/31581671
http://dx.doi.org/10.3390/cancers11101483

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